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In Hevea brasiliensis both the
2020-12-28

In Hevea brasiliensis, both the soluble PPase and the membrane-bound V-PPase are present in the latex; the soluble PPase is in the C-serum (cytosol) of the latex [6] and the V-PPase is on the tonoplast of the lutoid, a special vacuole in the laticifers of rubber trees [7]. The V-PPase on the lutoid
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We performed three baseline scans in two baboons and
2020-12-28

We performed three baseline scans in two baboons and one blocking study by administering 1 mg/kg (i.v) meloxicam 30 min prior to [C]TMI injection (injected activity 175.75 ± 18.5 MBq, mass of unlabeled TMI blood iwr synthesis barrier (BBB) and retained in brain with a somewhat heterogeneous pattern
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FLAG tag Peptide It is also meaningful to discuss whether VS
2020-12-28

It is also meaningful to discuss whether VSOR Cl− channel-induced apoptosis is correlated with the ER pathway. Thus, in this study, we sought to clarify the intrinsic relationship between VSOR Cl− channels and the level of ER stress-related proteins. The research results are as follows: the expressi
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Mohan et al found no improvement of
2020-12-28

Mohan et al. [8] found no improvement of the strength of the bricks due to addition of waste RHA. Hossain et al. [9] collected RHA from a local rice mill, where rice husk was burnt in an uncontrolled environment, and then used for replacement of clay in brick production. With inclusion of RHA water
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In a recent report Yoshihara and colleagues used
2020-12-28

In a recent report, Yoshihara and colleagues (2016) used transcriptomes derived from freshly isolated islets of 2-week-old neonatal, 6-week-old young adult, or 12-week-old adult mice to interrogate how maturation is regulated to acquire glucose responsiveness. The authors observed that estrogen-rela
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The present study also showed that EP deficiency and EP
2020-12-26

The present study also showed that EP2 deficiency and EP4 antagonism significantly suppressed psoriatic STA-21 mg in an imiquimod model. Notably, however, the combined EP2 deficiency and EP4 antagonism did not completely suppress ear swelling in this model, possibly because there is the IL-17–indepe
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Introduction Enzymes have higher selectivity specificity and
2020-12-26

Introduction Enzymes have higher selectivity, specificity and efficiency than chemical catalysts. Due to their properties and their green chemistry, biocatalysts are widely used in food, textile and pharmaceutical industry [1], [2]. A high efficient biocatalyst for industrial applications must be s
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br Early developments Historically the
2020-12-26

Early developments Historically, the advent of SMEPT can be traced to the 1980′s, where the first example of localized prodrug conversion was achieved using a judiciously placed enzyme – in order to achieve a localized feed of 5-fluorouracil (5-FU). Immobilization of E. coli-derived cytosine deam
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Regarding eicosanoid production iPLA VIA
2020-12-26

Regarding eicosanoid production, iPLA2-VIA appears, in general terms, not to play a major role in mediating this response in innate immunity and inflammation, as evidenced by the large number of studies highlighting the lack of effect of selective inhibition of the enzyme in stimulus-induced AA rele
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BMS 309403 Although many of the hepatic responses observed
2020-12-26

Although many of the hepatic responses observed on the first day of recovery attenuated over the course of the recovery period, minimal-to-mild centrilobular hepatocellular hypertrophy tended to persist. Mean absolute and relative liver weights had returned to control levels after 28 days of recover
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In conclusion this study indicated that D tripetala
2020-12-26

In conclusion, this study indicated that D. tripetala and A. melengueta extracts inhibited CYP 3A enzyme both in vitro and in vivo. Although these inhibitions may appear to be weak from the US FDA classification point of view, caution must be applied in the concurrent use of herbal preparations cont
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WES and validation by Sanger sequencing in
2020-12-25

WES and validation by Sanger sequencing in PNGS-252 revealed an apparent homozygous c.4C>G missense alteration (GenBank: NM_014176.3), resulting in the amino BIX 01294 substitution p.Gln2Glu (Figure 1A). This mutation must be very rare, because this is not listed in the NHLBI Exome Sequencing Proje
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br Conclusion The results of
2020-12-25

Conclusion The results of the current study show that boldness is associated with higher gene expression of drd2a, drd2b and oprd1b in zebrafish males. The results are correlational and additional experiments are needed to clarify the causal role of these receptors in zebrafish behavior. Confl
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br Introduction Identification and correct storage of semina
2020-12-25

Introduction Identification and correct storage of seminal stains are crucial for the investigation of sexual assault cases. Actually, undetected ‘cold’ cases involving sexual assault can be solved decades after investigations analysing DNA from stored evidences [1]. Recently, STR analysis and t
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This project was funded by the
2020-12-25

This project was funded by the Deutsche Forschungsgemeinschaft within FOR 2251 (project grants EB 285/2-1 and WI 3272/3-1) and in part by additional contributions from the Bundesministerium für Bildung und Forschung (D.I.S award Nos. BIOSCAT [05K12YE1]) and the Horizon 2020 programme of the European
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