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So what can be done by the
2019-04-29

So what can be done by the global Z-VDVAD-FMK to accelerate progress to achieve global targets? First, many cases of tuberculosis are clearly not officially diagnosed or treated. The so-called missing 3 million continue to be a major driver of the epidemic. This challenge was the theme of World Tube
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br INTRODUCCI N Con la incorporaci n
2019-04-29

INTRODUCCIÓN Con la incorporación de los derechos colectivos de los pueblos indígenas en la normatividad internacional de los derechos humanos, se inicia una nueva etapa en la conflictiva relación entre las bases fundacionales del poder político moderno y la diversidad cultural, en tanto aquellas
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Although successful conservative management has been reporte
2019-04-29

Although successful conservative management has been reported [9], the majority require surgical intervention to avoid devastating complications [1,10]. Several groups have demonstrated safety and efficacy of surgical intervention [1,4,10] and operative management may also shorten the length of hosp
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A limitation in assessing the economic
2019-04-29

A limitation in assessing the economic costs of outbreaks is that they order H-Lys(Ac)-OH.HCl only capture the impact on income. Fan and colleagues recently addressed this limitation by estimating the “inclusive” cost of pandemics: the sum of the cost in lost income and a dollar valuation of the c
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br Discussion Far field sensing of the
2019-04-28

Discussion Far-field sensing of the atrial electrogram by the ventricular lead is a rare but potentially serious complication of a VVI pacemaker in patients with complete heart block [1–3]. This phenomenon has usually been noted in a pacemaker where the tip of the pacing lead is located near the
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Radiation therapy RT is considered to be
2019-04-28

Radiation therapy (RT) is considered to be the standard treatment for cancer patients with symptomatic bone metastases [3,7,10,11]. Various studies have shown that approximately 60–70% of patients experience at least some degree of pain relief following RT, regardless of radiotherapy regime [5,7]. M
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The nuclear receptor liver X receptor LXR represents a
2019-04-28

The nuclear receptor liver X receptor (LXR) represents a promising therapeutic target for bile find out this here detoxification by enhancing the metabolism and elimination of bile acids as well as by reducing inflammation. Both pharmacological stimulation and genetic activation of LXR prevented LC
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br Introduction Since Reekers and Bolia introduced subintima
2019-04-28

Introduction Since Reekers and Bolia introduced subintimal angioplasty, the trans-subintimal route has become the preferred technique to advance the guidewire through a totally occluded and often heavily calcified lesion, especially in the aortoiliac segment. The technical failure was seen in 20–
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Amiodarone has been used in Japan for more than
2019-04-28

Amiodarone has been used in Japan for more than 5 years now since its approval in July 2007, and intravenous amiodarone has been widely used for life-threatening ventricular tachycardia in the setting of critical care medicine. However, only few reports have been published in the international liter
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5 alpha reductase Fig shows the percentage of patients
2019-04-28

Fig. 2 shows the percentage of patients with high D-dimer levels in relation to the CHA2DS2–VASc scores and BNP levels. None of the patients had a CHA2DS2–VASc score of 0. The BNP levels were elevated in 3 (38%) of the 8 patients with CHA2DS2–VASc scores of 1, and the D-dimer levels were elevated in
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Bisphosphonates are a well established standard of
2019-04-28

Bisphosphonates are a well-established, standard-of care treatment option to reduce the frequency and severity and time of onset of the skeletal related events (SREs) in patients with bone metastases due to either solid tumours or multiple myeloma [21–33]. From many years, BPs have been incorporated
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Both breast cancer and MM cause
2019-04-28

Both breast cancer and MM cause osteolytic lesions, inhibiting osteoblast differentiation and thereby tipping the balance in favour of osteoclastic activity. In contrast, prostate cancer predominantly causes osteoblastic bone disease. Interestingly, increased marrow adiposity has been associated wit
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In Jillian Pintye and colleagues from the Partners PrEP stud
2019-04-28

In Jillian Pintye and colleagues from the Partners PrEP study team present one of the largest and most comprehensive analyses of syphilis incidence in men and women and the effect of male circumcision. The investigators followed 4716 HIV-1 serodiscordant couples, of whom roughly 50% of the men were
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In the past three decades along with rapid
2019-04-28

In the past three decades, along with rapid economic growth in China, there has been a striking increase in alcohol consumption, greater than in most other parts of the world (). Although the melanocortin receptor drinking level in China used to be far lower than in many high-income and middle-inco
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br Las fuerzas Impulsoras de la
2019-04-28

Las fuerzas Impulsoras de la Internacionalización de la ciencia y la technología en América latina Los eLementos indicativos de la internacionalizacion de la ciencia y la tecnología en América Latina Debates ytensiones en torno de la internacionalización de la ciencia y la technología en Amé
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